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1

Development of HVAC system simulation tool for life cycle energy management Part 1: Concept of life cycle energy management and outline of the developed simulation tool

Masayasu Ito, Shuzo Murakami, Masaya Okumiya, Shigeru Tokita, Hideharu Niwa, Yoshibumi Suigihara, Hideki Tanaka, Takeshi Watanabe, Mika Yoshinaga, Katsuhiro Miura, Hideharu Komoda, Yuji Miyajima, Tets

Journal:

Building Simulation

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008

2

Experimental study on the channel effect in emulsion explosives

Fumihiko Sumiya, Kazushi Tokita, Masashi Nakano, Yuji Ogata, Yuji Wada, Masahiro Seto, Kunihisa Katsuyama, Shigeru Itoh

Journal:

Journal of Materials Processing Technology

Year:

1999

Language:

english

File:

PDF, 93 KB

english, 1999

3

Normal Embryonic Stages of the Chinese Softshelled Turtle Pelodiscus sinensis (Trionychidae)

Tokita, Masayoshi, Kuratani, Shigeru

Journal:

Zoological Science

Year:

2001

Language:

english

File:

PDF, 936 KB

english, 2001

4

Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity

Miles D. Thompson, David E. Comings, Rashid Abu-Ghazalah, Yousef Jereseh, Leo Lin, Judy Wade, Takeshi Sakurai, Shigeru Tokita, Tetsuo Yoshida, Hirokazu Tanaka, Masashi Yanagisawa, W. McIntyre Burnham,

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

5

Observation of a new in-situ optical monitoring signal with monolayer resolution in metalorganic molecular beam epitaxy and metalorganic vapor phase epitaxy of wide-gap II–VI compounds

Akihiko Yoshikawa, Masakazu Kobayashi, Shigeru Tokita

Journal:

Journal of Crystal Growth

Year:

1994

Language:

english

File:

PDF, 502 KB

english, 1994

6

Surface reaction mechanism in MOMBE-ALE of ZnSe and CdSe as determined by a new in-situ optical probing method

Akihiko Yoshikawa, Masakazu Kobayashi, Shigeru Tokita

Journal:

Applied Surface Science

Year:

1994

Language:

english

File:

PDF, 549 KB

english, 1994

7

Synthesis, structure–activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H3 receptor inverse agonists

Takahide Sasaki, Toshiyuki Takahashi, Tsuyoshi Nagase, Takashi Mizutani, Sayaka Ito, Yuko Mitobe, Yasuhisa Miyamoto, Maki Kanesaka, Ryo Yoshimoto, Takeshi Tanaka, Norihiro Takenaga, Shigeru Tokita, Na

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 982 KB

english, 2009

8

Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors

Minoru Kameda, Makoto Ando, Chisato Nakama, Kensuke Kobayashi, Hiroshi Kawamoto, Sayaka Ito, Tomoki Suzuki, Takeshi Tani, Satoshi Ozaki, Shigeru Tokita, Nagaaki Sato

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 906 KB

english, 2009

9

Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors

Takahide Sasaki, Tsuyoshi Nagase, Toshiyuki Takahashi, Akira Nagumo, Ken Shimamura, Yasuhisa Miyamoto, Hidefumi Kitazawa, Maki Kanesaka, Ryo Yoshimoto, Katsumi Aragane, Shigeru Tokita, Nagaaki Sato

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 993 KB

english, 2009

10

Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists

Yuji Haga, Sayaka Mizutani, Akira Naya, Hiroyuki Kishino, Hisashi Iwaasa, Masahiko Ito, Junko Ito, Minoru Moriya, Nagaaki Sato, Norihiro Takenaga, Akane Ishihara, Shigeru Tokita, Akio Kanatani, Norika

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.07 MB

english, 2011

11

Synthesis and evaluation of a spiro-isobenzofuranone class of histamine H3 receptor inverse agonists

Makoto Jitsuoka, Daisuke Tsukahara, Sayaka Ito, Takeshi Tanaka, Norihiro Takenaga, Shigeru Tokita, Nagaaki Sato

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

12

Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists

Takashi Mizutani, Tsuyoshi Nagase, Sayaka Ito, Yasuhisa Miyamoto, Takeshi Tanaka, Norihiro Takenaga, Shigeru Tokita, Nagaaki Sato

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 665 KB

english, 2008

13

Development of a selective and potent radioactive ligand for histamine H3 receptors: A compound potentially useful for receptor occupancy studies

Yuko Mitobe, Sayaka Ito, Takashi Mizutani, Tsuyoshi Nagase, Nagaaki Sato, Shigeru Tokita

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 241 KB

english, 2009

14

Design, synthesis and evaluation of a novel cyclohexanamine class of neuropeptide Y Y1 receptor antagonists

Kaimei Cho, Makoto Ando, Kensuke Kobayashi, Hiroshi Miyazoe, Toshiaki Tsujino, Sayaka Ito, Tomoki Suzuki, Takeshi Tanaka, Shigeru Tokita, Nagaaki Sato

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.76 MB

english, 2009

15

Development of a potent and selective GPR7 (NPBW1) agonist: a systematic structure–activity study of neuropeptide B

Maki Kanesaka, Masao Matsuda, Atsushi Hirano, Kenichi Tanaka, Akio Kanatani, Shigeru Tokita

Journal:

Journal of Peptide Science

Year:

2007

Language:

english

File:

PDF, 130 KB

english, 2007

16

Inverse agonist histamine H3 receptor PET tracers labelled with carbon-11 or fluorine-18

Terence G. Hamill, Nagaaki Sato, Makoto Jitsuoka, Shigeru Tokita, Sandra Sanabria, Waisi Eng, Christine Ryan, Stephen Krause, Norihiro Takenaga, Shil Patel, Zhizhen Zeng, David Williams Jr., Cyrille S

Journal:

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

17

Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice

Junko Ito, Masahiko Ito, Hirohide Nambu, Toru Fujikawa, Kenichi Tanaka, Hisashi Iwaasa, Shigeru Tokita

Journal:

Cell and Tissue Research

Year:

2009

Language:

english

File:

PDF, 267 KB

english, 2009

18

Development of a High-Density Assay for Long-Chain Fatty Acyl-CoA Elongases

Hidefumi Kitazawa, Yasuhisa Miyamoto, Ken Shimamura, Akira Nagumo, Shigeru Tokita

Journal:

Year:

2009

Language:

english

File:

PDF, 453 KB

english, 2009

19

Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography

Yasuhisa Miyamoto, Ryo Yoshimoto, Mariko Yumoto, Akane Ishihara, Kazuhiko Takahashi, Hidehito Kotani, Akio Kanatani, Shigeru Tokita

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 474 KB

english, 2004

20

Studies on reflexes mediated by N. laryngicus cranialis internus on heart, vessels and respiration

Kikuji Tokita, Miyako Ohmoto, Shigeru Yashiki, Ryuta Ito

Journal:

Journal of Neural Transmission

Year:

1966

Language:

english

File:

PDF, 314 KB

english, 1966

21

Detailed pharmacological characterization of GT-2331 for the rat histamine H3 receptor

Sayaka Ito, Ryo Yoshimoto, Yasuhisa Miyamoto, Yuko Mitobe, Takao Nakamura, Akane Ishihara, Douglas J. MacNeil, Akio Kanatani, Shigeru Tokita

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 295 KB

english, 2006

22

Distinctive role of central histamine H3 receptor in various orexigenic pathways

Ryo Yoshimoto, Akio Kanatani, Shigeru Tokita

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

23

Impaired drinking response in histamine H3 receptor knockout mice following dehydration or angiotensin-II challenge

Ryo Yoshimoto, Yasuhisa Miyamoto, Kazuhiko Takahashi, Hidehito Kotani, Akio Kanatani, Shigeru Tokita

Journal:

Pharmacology Biochemistry and Behavior

Year:

2006

Language:

english

File:

PDF, 245 KB

english, 2006

24

Anti-idiotypic monoclonal antibody recognizes a consensus recognition site for phosphatidylserine in phosphatidylserine-specific monoclonal antibody and protein kinase C

Farooq Reza, Koji Igarashi, Shigeru Tokita, Kenji Asai, Junken Aoki, Yoshinori Asaoka, Masato Umeda, Keizo Inoue

Journal:

Year:

1994

Language:

english

File:

PDF, 615 KB

english, 1994

25

Development of a potent and selective GPR7 agonist: A systematic structure–activity study of neuropeptide B

Maki Kanesaka, Masao Matsuda, Atsushi Hirano, Kenichi Tanaka, Akio Kanatani, Shigeru Tokita

Journal:

Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

26

(−)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells

Masahiko Ito, Junko Ito, Hidefumi Kitazawa, Ken Shimamura, Takehiro Fukami, Shigeru Tokita, Kenichiro Shimokawa, Kaoru Yamada, Akio Kanatani, Daisuke Uemura

Journal:

Year:

2009

Language:

english

File:

PDF, 677 KB

english, 2009

27

Identification of a stable chemerin analog with potent activity toward ChemR23

Ken Shimamura, Masao Matsuda, Yasuhisa Miyamoto, Ryo Yoshimoto, Toru Seo, Shigeru Tokita

Journal:

Year:

2009

Language:

english

File:

PDF, 536 KB

english, 2009

28

Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice: Molecular Genetic Dissection of Non-REM and REM Sleep Regulatory Processes

Jon T. Willie, Richard M. Chemelli, Christopher M. Sinton, Shigeru Tokita, S.Clay Williams, Yaz Y. Kisanuki, Jacob N. Marcus, Charlotte Lee, Joel K. Elmquist, Kristi A. Kohlmeier, Christopher S. Leona

Journal:

Year:

2003

Language:

english

File:

PDF, 796 KB

english, 2003

29

Repulsive Guidance Molecule-a and Demyelination: Implications for Multiple Sclerosis

Takekazu Kubo, Shigeru Tokita, Toshihide Yamashita

Journal:

Journal of Neuroimmune Pharmacology

Year:

2012

Language:

english

File:

PDF, 115 KB

english, 2012

30

Effective induction of anti-phospholipid and anticoagulant antibodies in normal mouse

Kouji Igarashi, Masato Umeda, Shigeru Tokita, Kyung Soo Nam, Keizo Inoue

Journal:

Thrombosis Research

Year:

1991

Language:

english

File:

PDF, 958 KB

english, 1991

31

Characterization of [18F]Y1-973, a novel PET tracer for the neuropeptide Y Y1 receptor (NPY Y1), in rhesus monkey

Eric Hostetler, Sandra Sanabria, Hong Fan, Minoru Kameda, Makato Ando, Zhizhen Zeng, Stacey O'Malley, Patricia Miller, Liza Gantert, David Williams, Shigeru Tokita, Nagaaki Sato, Satoshi Ozaki, Hisash

Journal:

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

32

Anti-Idiotypic Antibody Identifies a Consensus Recognition Site for Phosphatidylserine Common to Protein Kinase C and Other Cellular Phosphatidylserine-Binding Proteins

KOJI IGARASHI, MASATO UMEDA, REZA FAROOQ, SHIGERU TOKITA, YOSHINORI ASAOKA, YASUTOMI NISHIZUKA, KEIZO INOUE

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 157 KB

english, 1993

33

Synthesis and Biological Evaluation of a Novel 3-Sulfonyl-8-azabicyclo[3.2.1]octane Class of Long Chain Fatty Acid Elongase 6 (ELOVL6) Inhibitors

Nagase, Tsuyoshi, Takahashi, Toshiyuki, Sasaki, Takahide, Nagumo, Akira, Shimamura, Ken, Miyamoto, Yasuhisa, Kitazawa, Hidefumi, Kanesaka, Maki, Yoshimoto, Ryo, Aragane, Katsumi, Tokita, Shigeru, Sato

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 818 KB

english, 2009

34

Synthesis and Evaluation of a Novel Indoledione Class of Long Chain Fatty Acid Elongase 6 (ELOVL6) Inhibitors

Takahashi, Toshiyuki, Nagase, Tsuyoshi, Sasaki, Takahide, Nagumo, Akira, Shimamura, Ken, Miyamoto, Yasuhisa, Kitazawa, Hidefumi, Kanesaka, Maki, Yoshimoto, Ryo, Aragane, Katsumi, Tokita, Shigeru, Sato

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

35

Fliplike Motion in the Thalidomide Dimer: Conformational Analysis of ( R )-Thalidomide Using Vibrational Circular Dichroism Spectroscopy

Izumi, Hiroshi, Futamura, Shigeru, Tokita, Nakako, Hamada, Yoshiaki

Journal:

Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 195 KB

english, 2007

36

High-Throughput Assay for Long Chain Fatty Acyl-CoA Elongase Using Homogeneous Scintillation Proximity Format

Shimamura, Ken, Miyamoto, Yasuhisa, Kitazawa, Hidefumi, Kobayashi, Tsutomu, Kotani, Hidehito, Tokita, Shigeru

Journal:

Assay and Drug Development Technologies

Year:

2009

Language:

english

File:

PDF, 1.73 MB

english, 2009

37

Experimental Studies on Longitudinal Mode Characteristics of a Hollow Cathode He–Cd + White Light Laser

Xu, Guang, Fujii, Kan-ichi, Nakayama, Shigeru, Honma, Akira, Uchiyama, Yoshihiro, Tokita, Yasuhiro, Hanazawa, Yoshihiro

Journal:

Japanese Journal of Applied Physics

Year:

1997

File:

PDF, 939 KB

1997

38

Characterization of MCH-mediated obesity in mice

Ito, Masahiko, Gomori, Akira, Ishihara, Akane, Oda, Zenjun, Mashiko, Satoshi, Matsushita, Hiroko, Yumoto, Mariko, Ito, Makoto, Sano, Hideki, Tokita, Shigeru, Moriya, Minoru, Iwaasa, Hisashi, Kanatani,

Journal:

AJP Endocrinology and Metabolism

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

39

Enhancement of chemosensitivity toward anticancer drugs by high expression of caspase-1 in NIH 3T3 cells

Hiwasa, Takaki, Tokita, Hisashi, Sakiyama, Shigeru, Nakagaware, Akira

Journal:

Anti-Cancer Drugs

Year:

1998

File:

PDF, 447 KB

1998

40

Hemodynamic and Cardiac Neurotransmitter-releasing Effects in Conscious Dogs of Attention- and Wake-promoting Agents: A Comparison of d-Amphetamine, Atomoxetine, Modafinil, and a Novel Quinazolinone H3 Inverse Agonist

Lynch, Joseph, Regan, Christopher, Stump, Gary, Tannenbaum, Pamela, Stevens, Joanne, Bone, Ashleigh, Gilberto, David, Johnson, Colena, Fujino, Naoko, Takenaga, Norihiro, Tokita, Shigeru, Nagase, Tsuyo

Journal:

Journal of Cardiovascular Pharmacology

Year:

2009

Language:

english

File:

PDF, 240 KB

english, 2009

41

Solid-Surface Fluorescence Characteristics and X-Ray Crystal Structures of Inclusion Compounds of Imidazoanthraquinol-type Fluorescent Host with Ethanol and 1,4-Dioxane

Yoshida, Katsuhira, Tachikawa, Tatsuya, Yamasaki, Jun, Watanabe, Shigeru, Tokita, Sumio

Journal:

Chemistry Letters

Year:

1996

File:

PDF, 335 KB

1996

42

10.1254/fpj.129.119

Tokita, Shigeru

Journal:

Folia Pharmacologica Japonica

Year:

2007

File:

PDF, 332 KB

2007

43

Regulation mechanism of autonomic nervous functions (XXVIII)

TOKITA, Kikuji, OHOMOTO, Miyako, YOSHIKATA, Manabu, YASHIKI, Shigeru, NAKAMURA, Yuzo, ISHIKAWA, Eiji, TAGUCHI, Mitsugu, MATONO, Kiyohiro, MURAKI, Kazuo, SAI, Shoroku

Journal:

Folia Pharmacologica Japonica

Year:

1964

File:

PDF, 565 KB

1964

44

Regulation mechanism of autonomic function on N. 1. cr. int. Chapter 2. On respiratory reflex

TOKITA, Kikuji, OHMOTO, Miyako, YASHIKI, Shigeru, HIROSHIBA, Yoshikata, YAGI, Yasuke, AYABE, Makoto, MURAKI, Kazuo

Journal:

Folia Pharmacologica Japonica

Year:

1963

File:

PDF, 1.09 MB

1963

45

Blood-pressure regulation system (I)

TOKITA, Kikuji, NISHIMUTA, Sukeaki, KAWASAKI, Yoshinori, NAKAMURA, Naoyoshi, KIMURA, Takeichi, SAITO, Kozo, YONEMITSU, Shinichiro, YASHIKI, Shigeru, NOZAWA, Chikukei, SATO, Kaya

Journal:

Folia Pharmacologica Japonica

Year:

1958

File:

PDF, 1.42 MB

1958

46

Regulation mechanism of the autonomic nervous functions. (XXIV)

TOKITA, Kikuji, KAWAMURA, Hironori, OHMOTO, Miyako, YASHIKI, Shigeru, OTSUKI, Toshie, EBISAWA, Kenji, NAKAMURA, Uzo, IWANAGA, Yukimasa, YONEMITSU, Shiniro, TAGUCHI, Mitsugu, ISHIKAWA, Eiji, MURAKI, Ka

Journal:

Folia Pharmacologica Japonica

Year:

1964

File:

PDF, 842 KB

1964

47

Recent Advances in Molecular Pharmacology of the Histamine Systems: Physiology and Pharmacology of Histamine H3 Receptor: Roles in Feeding Regulation and Therapeutic Potential for Metabolic Disorders

Tokita, Shigeru, Takahashi, Kazuhiko, Kotani, Hidehito

Journal:

Journal of Pharmacological Sciences

Year:

2006

Language:

english

File:

PDF, 167 KB

english, 2006

48

Heart-rate regulation system in rabbit

TOKITA, Kikuji, NISHIMUTA, Sukeaki, KAWASAKI, Yoshinori, NAKAMURA, Naoyoshi, KIMURA, Takeichi, SAITO, Kozo, YONEMITSU, Shinichiro, YASHIKE, Shigeru

Journal:

Folia Pharmacologica Japonica

Year:

1958

File:

PDF, 2.30 MB

1958

49

Mechanism of autonomic nerve regulation (V) Mechanism of blood pressure regulation (II)

TOKITA, Kikuji, NISHIMUTA, Sukeaki, KAWASAKI, Yoshinori, NAKAMURA, Naoyoshi, SAITO, Kozo, KIMURA, Takeichi, YONEMITSU, Shinichiro, YASHIKI, Shigeru, NOZAWA, Chikukei, SATO, Kaya

Journal:

Folia Pharmacologica Japonica

Year:

1958

File:

PDF, 1.44 MB

1958

50

Comparative studies on the ECG of whale, human, rabbit and tortoise

TOKITA, Kikuji, ITO, Ryuta, NISHIMUTA, Sukeaki, KAWASAKI, Yoshinori, NAKAMURA, Naoyoshi, SAITO, Kozo, HENOMATSU, Hiroshi, NAGAOKA, Toshio, KAMATA, Toshio, TAKASHIMA, Keishio, KANDA, Shigeru, ISOGAI, S

Journal:

Folia Pharmacologica Japonica

Year:

1961

File:

PDF, 296 KB

1961